Stimulating the Auricular Branch of the Vagus Nerve


Zero Point™ is a non-invasive, battery-operated device designed to transcutaneously stimulate the auricular branch of the vagus nerve (ABVN) to aid in reducing the symptoms of various chronic diseases and disorders. This is accomplished by stimulating a cutaneous area on the outer ear.

The device is worn similar to headphones and is composed of a handheld generator and earpiece. The earpiece makes electrical contact with the skin via disposable hydrogel electrodes.

Nexeon is pursuing multiple indications for the Zero Point technology. Clinical activities are in progress using Zero Point to treat Atrial Fibrillation and Opioid Withdrawal.

Indication Milestone
Opioid withdrawal pilot Complete 2018
Opioid withdrawal pivotal Complete 2019
Opioid FDA approval 2020
Atrial fibrillation pilot Funded, complete in early 2019
Atrial fibrillation pivotal Funded, complete in early 2020
Atrial fibrillation CE Mark 2020