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eyebipo.jpgR&D Special Focus: Bioelectronics

June 30, 2017 - by Laura Panjwani of R&D Magazine

Non-invasive bioelectronic devices offer the potential to reduce surgery risk and recovery time. However, electronics can also be used internally, and have the potential to replace or reduce the number of pharmaceutical interventions required. They can be helpful in areas where pharmaceutical interventions are not effective enough. One area showing promise is deep brain stimulation, a practice used to treat neurological disorders like Parkinson’s disease and essential tremor. To learn more about this, R&D Magazine spoke with Will Rosellini, a retired professional minor-league pitcher whose interest in the nervous system led him to get six graduate degrees and start Nexeon MedSystems, a bioelectronics company.

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From Baseball to Bioelectronics: Pro Pitcher Turned CEO Scientist Explains Deep Brain Stimulation Tech

June 15, 2017 by Laura Panjwani of R&D Magazine

"Right now there has been almost 135,000 patients implanted with a [deep brain stimulation] device, but not ours. It is a very safe, well-tolerated procedure. Patients regain almost the level of function they had before their disease. The challenge now is— how do we make the procedure easier for the neurologist to maintain the patient in the therapeutic window? The question really is not will it work, the question it is how do we make it better so we can get more patients implanted."

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Nexeon-Infographic-cropped-1-pager-executive-summary-company-description.pngAlternative Paths to Public Markets: Nexeon's Form 10 IPO & Capital Consciousness

May 30, 2017 by Javier Hasse of BenZingA

...Rosellini explained how Nexeon was going to enter the public markets through an alternative mechanism that does not involve the same steps as most IPOs in the U.S.

Following the steps of companies like Intel Corporation, which raised only $5 million when it went public, Nexeon will try to be “really capital-conscious and prove out the business at each stage,” the CEO said. “That way, we will be able to look at our investors and tell them we thought about them, as opposed to raising a ton of VC [venture capital] money at crazy valuations, not wanting to go public, continuing to try to drive and grow and get market share, but never getting to profitability.”

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Nexeon CEO on the Brain Chip Targeting Parkinson's, Lou Gehrig's Disease, and Other "Cyborg" Technologies

May 29, 2017 by Javier Hasse of BenZingA

Nexeon is currently producing a deep brain stimulation device, expected to launch in Europe in the first quarter of 2018. The company’s first commercial product basically consists of an implant, similar to a pacemaker, which connects via Bluetooth to an Apple Inc. iPad clinical programmer. This allows users to turn the device on and off, steer the current to the places that need it, and even record local field potentials, “which tell them what the brain is doing, and when it is being stimulated or it’s going into a tremor state,” Rosellini explained.

Nexeon’s product will initially target Parkinson’s disease-affected brains. However, the company is also conducting preclinical studies in dysphasia from ALS, "Lou Gehrig’s disease," and recently completed a mouse study for overactive bladder and asthma, with positive results.

“We expect to move into other markets with the device once we launch a successful DBS product,” Rosellini added.

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